“Stimuli-Responsive Ocular Inserts for Sustained drug Delivery system"
Abdul Rajik, Pankaj Prajapati, Gopal Chaudhry · International Journal for Multidisciplinary Research (IJFMR) · 2025
Stimuli-responsive ocular inserts can deliver medication for eye diseases by adjusting release based on body signals, improving treatment efficacy.
Plain English summary
Why this matters
Key findings
- Inserts release medication based on pH changes in the eye.
- 80% of the drug is released at a pH of 6.5, indicating responsiveness to inflammation.
- The inserts are safe for eye surface cells.
- The system allows for sustained drug delivery over 14 days.
- It could improve patient compliance with treatment regimens.
What's new
The use of a gel that reacts to pH changes for sustained drug delivery in ocular inserts is a new approach in treating chronic eye inflammation.
Limitations
The abstract does not provide details on long-term effects or clinical trials beyond laboratory testing.
Commercial context
The technology is still in the laboratory testing phase and has not yet been commercialized.
Publication
- Publisher
- International Journal for Multidisciplinary Research (IJFMR)
- Publication date
- November 9, 2025
- Research type
- Paper
Tags
More on Stimuli-Responsive Materials
See all →Stimuli-Responsive Nanocarriers for Targeted Drug Delivery: Design Strategies, Clinical Progress, and Translational Challenges
Stimuli-responsive nanocarriers are advanced systems designed to release drugs in response to specific biological or external signals, enhancing targeted drug delivery.
Transformer-Based Deep Learning Framework for Predicting Stimuli-Responsive Release Profiles in Nano-Drug Delivery Systems
A Transformer-based deep learning framework predicts drug release profiles from stimuli-responsive nanocarriers with high accuracy.
Smart Stimuli-responsive Nanocarriers in Nanotechnology-based Cancer Diagnosis and Treatment
Smart stimuli-responsive nanocarriers enhance cancer treatment by enabling targeted drug delivery and reducing side effects.
Stimuli-Responsive Nanocarriers for Targeted Drug Delivery: A Review
Smart nanocarriers enhance targeted drug delivery by responding to specific stimuli, improving therapeutic efficacy while minimizing side effects.
Next Generation of Drug Delivery: Stimuli Responsive Drug Delivery Overview
Smart drug delivery systems enhance therapeutic effectiveness by providing controlled and targeted drug release in response to specific stimuli.
Light-activated gel could impact wearables, soft robotics, and more
A light-activated, biocompatible soft gel is reported to dramatically change its conductivity, supporting ionotronics-style interfaces for wearables and soft robotics.
Recently published
Latest research →Bio-inspired re-entrant honeycomb metamaterial with programmable dual-plateau mechanical response
A bio-inspired re-entrant honeycomb mechanical metamaterial is described as having a programmable dual-plateau mechanical response.
Modelling the thermo-mechanical responses and shape recovery performance of particle-reinforced shape memory polymer composites in cold and hot programming
A study focused on modeling thermo-mechanical behavior and shape recovery of particle-reinforced shape-memory polymer composites when programmed in cold versus hot conditions.
An electrically isolated Josephson junction array as a tunable metamaterial
This study explores a tunable electromagnetic metamaterial based on an electrically isolated Josephson junction array, demonstrating its nonlinear response.
Functional Shape Recovery Response of Heat-Treated NiTiCu SHAPE Memory Alloy Wire
Heat treatment of NiTiCu shape memory alloy wires enhances their shape recovery response, achieving a high recovery ratio.