Stimuli-Responsive Nanocarriers for Targeted Drug Delivery: A Review
Vishal H. Thorat, Shagufta J. Pathan, Pramod B. Patil, Pranil B. Toraskar, Sachin S. Mali, Samiksha V. Kamble · Dr. Yashwant Research Labs Pvt. Ltd. · 2026
Smart nanocarriers enhance targeted drug delivery by responding to specific stimuli, improving therapeutic efficacy while minimizing side effects.
Plain English summary
Why this matters
Key findings
- Smart nanocarriers can release drugs based on internal stimuli like tumor microenvironments.
- External stimuli such as temperature and light can also trigger drug release.
- These systems enhance therapeutic efficacy while minimizing side effects.
- Dual- or multi-stimuli responsive systems improve targeting accuracy.
- Challenges remain in complexity, stability, scalability, and regulatory approval.
What's new
The review highlights the advancements in stimuli-responsive nanocarriers specifically designed for targeted drug delivery in cancer therapy.
Limitations
The abstract mentions ongoing challenges related to complexity, stability, scalability, and regulatory approval that hinder clinical translation.
Commercial context
The abstract does not provide information on commercial availability or readiness.
Publication
- Publisher
- Dr. Yashwant Research Labs Pvt. Ltd.
- Publication date
- May 5, 2026
- Research type
- Paper
Tags
More on Stimuli-Responsive Materials
See all →Stimuli-Responsive Nanocarriers for Targeted Drug Delivery: Design Strategies, Clinical Progress, and Translational Challenges
Stimuli-responsive nanocarriers are advanced systems designed to release drugs in response to specific biological or external signals, enhancing targeted drug delivery.
Transformer-Based Deep Learning Framework for Predicting Stimuli-Responsive Release Profiles in Nano-Drug Delivery Systems
A Transformer-based deep learning framework predicts drug release profiles from stimuli-responsive nanocarriers with high accuracy.
Smart Stimuli-responsive Nanocarriers in Nanotechnology-based Cancer Diagnosis and Treatment
Smart stimuli-responsive nanocarriers enhance cancer treatment by enabling targeted drug delivery and reducing side effects.
Next Generation of Drug Delivery: Stimuli Responsive Drug Delivery Overview
Smart drug delivery systems enhance therapeutic effectiveness by providing controlled and targeted drug release in response to specific stimuli.
Light-activated gel could impact wearables, soft robotics, and more
A light-activated, biocompatible soft gel is reported to dramatically change its conductivity, supporting ionotronics-style interfaces for wearables and soft robotics.
Stimuli-Responsive Drug Delivery Platforms Design Strategies and Therapeutic Applications
This research explores advanced stimuli-responsive drug delivery systems that enhance targeted therapy and precision medicine.
Recently published
Latest research →Bio-inspired re-entrant honeycomb metamaterial with programmable dual-plateau mechanical response
A bio-inspired re-entrant honeycomb mechanical metamaterial is described as having a programmable dual-plateau mechanical response.
Modelling the thermo-mechanical responses and shape recovery performance of particle-reinforced shape memory polymer composites in cold and hot programming
A study focused on modeling thermo-mechanical behavior and shape recovery of particle-reinforced shape-memory polymer composites when programmed in cold versus hot conditions.
An electrically isolated Josephson junction array as a tunable metamaterial
This study explores a tunable electromagnetic metamaterial based on an electrically isolated Josephson junction array, demonstrating its nonlinear response.
Functional Shape Recovery Response of Heat-Treated NiTiCu SHAPE Memory Alloy Wire
Heat treatment of NiTiCu shape memory alloy wires enhances their shape recovery response, achieving a high recovery ratio.