The Convergence of Biology and Material Science: Biomolecule-Driven Smart Drug Delivery Systems
Yaqin Hou, Xiaolei Yu · MDPI AG · 2025
Biomolecule-driven smart materials are revolutionizing drug delivery by enabling active, programmable responses to specific biological cues.
Plain English summary
Why this matters
Key findings
- Biomolecule-driven systems transition drug delivery to active, programmable interventions.
- Systems can respond to both endogenous and exogenous triggers.
- Unique design spaces are offered by DNA nanotechnology, peptides, and polysaccharides.
- Key applications include oncology, inflammatory diseases, and gene therapy.
- Challenges include biocompatibility, scalability, and regulatory issues.
What's new
The review highlights the integration of biomolecules in smart materials for drug delivery, emphasizing their programmable nature and responsiveness to specific biological cues.
Limitations
The abstract does not provide specific experimental results or data, focusing instead on a review of existing literature and concepts.
Commercial context
The abstract does not mention any commercial applications or readiness.
Publication
- Publisher
- MDPI AG
- Publication date
- September 28, 2025
- Research type
- Paper
- License
- https://creativecommons.org/licenses/by/4.0/
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