Smart Hydrogel Systems for Skin Fibrosis: Rational Design, Mechanisms, and Therapeutic Applications
Ranyu Sun, Zhaojian Wang, Xiao Long · Oxford University Press (OUP) · 2026
This review discusses the design and therapeutic potential of smart hydrogels for treating skin fibrosis.
Plain English summary
Why this matters
Key findings
- Smart hydrogels can sense and respond to changes in the fibrotic microenvironment.
- They enable controlled delivery of therapeutic agents.
- Incorporation of bioactive molecules and nanomaterials enhances their effectiveness.
- Current challenges in clinical translation are discussed.
- Future perspectives for safer and more effective therapies are outlined.
What's new
The review emphasizes the unique capabilities of smart hydrogels to adapt to pathological changes, distinguishing them from conventional scaffolds.
Limitations
The abstract mentions challenges in clinical translation but does not provide specific details on these challenges or the extent of current limitations.
Commercial context
The abstract does not provide information on the commercial status of the technologies discussed.
Publication
- Publisher
- Oxford University Press (OUP)
- Publication date
- July 31, 2026
- Research type
- Paper
- License
- https://creativecommons.org/licenses/by/4.0/
Tags
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