Research on the application of biomaterial-based responsive hydrogels in the tumor microenvironment
Wanrong Yue, Xiaoyu Zhu, Ming Wu, Wenyue Qiang, Yixin Yang, Ziyun Zhang +3 · PeerJ · 2025
Responsive hydrogels show promise in enhancing cancer treatment by adapting to the tumor microenvironment.
Plain English summary
Why this matters
Key findings
- Responsive hydrogels are biocompatible and biodegradable.
- They can respond to environmental stimuli such as pH and temperature.
- These materials can enhance targeted tumor therapy and controlled drug delivery.
- Challenges include hydrogel design, safety, and clinical translation.
- Future research aims to optimize interactions with tumor-specific conditions.
What's new
The review provides a comprehensive assessment of the current landscape of responsive hydrogels specifically in the context of the tumor microenvironment.
Limitations
The abstract mentions challenges in hydrogel design and clinical translation but does not provide specific examples or solutions.
Commercial context
The abstract does not indicate any commercial availability or readiness of the discussed materials.
Publication
- Publisher
- PeerJ
- Publication date
- July 8, 2025
- Research type
- Article
- License
- https://creativecommons.org/licenses/by/4.0/
Tags
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